At Healthy Male, we regularly review and summarise research articles published in scientific and medical journals that are relevant to the growing evidence-base in male reproductive and sexual health.

Our research reviews are for anyone with a professional or personal interest in male health, and cover a range of topics, including prostate disease, prostate cancer, testicular cancer, male infertility, androgen deficiency, and erectile dysfunction, as well as other emerging areas that are relevant to the health and wellbeing of Australian men.

Review date Title Category Link
April 2021 Research to refine surveillance after testicular cancer treatment hampered by lower-than-expected rates of relapse Testicular cancer Reference
March 2021 Undiagnosed prediabetes status is associated with a reduced effectiveness of PDE5i in men with erectile dysfunction Erectile dysfunction Reference
February 2021 The future of focal therapy for prostate cancer treatment Prostate cancer See review
September 2020 Simple visual cues can make expectant fathers feel more included in prenatal care, and motivate them to become better dads Fatherhood Reference
August 2020 Expression of small non-coding RNAs in urinary exosomes classifies prostate cancer into indolent and aggressive disease Prostate cancer Reference
August 2020 What do Australian GPs really think about providing fertility and preconception health advice to men? Male fertility and fatherhood Reference
August 2020 Pharmacoepidemiology of testosterone: Impact of reimbursement policy on curbing off-label prescribing Androgen deficiency and testosterone Reference
January 2020 High rates of active chlamydia infection in the testes of infertile men Male fertility and fatherhood Reference
July 2019 What influences men's decision making for treatment of localised prostate cancer? Prostate cancer Reference
May 2019 Nerve grafting procedure restores erectile function after surgery for prostate cancer Erectile dysfunction Reference
May 2019 Environmental chemicals impact the reproductive health of young men Male fertility and fatherhood Reference
March 2019 Factors influencing treatment decisions and decision support needs for patients diagnosed with localised prostate cancer Prostate disease Reference
February 2019 Reduced Testicular Steroidogenesis and Increased Semen Oxidative Stress in Male Partners as Novel Markers of Recurrent Miscarriage Male fertility and fatherhood Reference
January 2019 Early-Life Alcohol Intake and High-Grade Prostate Cancer: Results from an Equal-Access, Racially Diverse Biopsy Cohort Prostate disease Reference
December 2018 Health consequences of androgenic anabolic steroid use Adolescent and young adult males Reference
October 2018 Genetic variation in the SIM1 locus is associated with erectile dysfunction Erectile dysfunction Reference
September 2018 Cross-sex Hormones and Acute Cardiovascular Events in Transgender Persons Transgender health Reference
August 2018 Patient-derived models of abiraterone- and enzalutamide-resistant prostate cancer reveal sensitivity to ribosome-directed therapy Prostate disease Reference
June 2018 Inactivation of CDK12 Delineates a Distinct Immunogenic Class of Advanced Prostate Cancer Prostate disease Reference
May 2018 MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis Prostate disease Reference
February 2018 Long-term Psychological and Quality-of-life Effects of Active Surveillance and Watchful Waiting After Diagnosis of Low-risk Localised Prostate Cancer Prostate disease Reference
November 2017 Men’s perceptions of prostate cancer diagnosis and care: insights from qualitative interviews in Victoria, Australia Prostate disease Reference
October 2017 Follow-up of prostatectomy versus observation for early prostate cancer Prostate disease Reference
July 2017 Temporal trends in sperm count: a systematic review and meta-regression analysis Male fertility and fatherhood Reference
May 2017 Testosterone treatment and coronary artery plaque volume in older men with low testosterone Androgen deficiency and testosterone Reference
February 2017 Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS): a paired validating confirmatory study Prostate disease Reference
December 2016 Men’s knowledge of their own fertility: a population-based survey examining the awareness of factors that are associated with male infertility Male fertility and fatherhood Reference
November 2016 Causes of male infertility: a 9-year prospective monocentre study on 1737 patients with reduced total sperm counts Male fertility and fatherhood Reference
October 2016 Risk of erectile dysfunction associated with use of 5-α reductase inhibitors for benign prostatic hyperplasia or alopecia: population based studies using the Clinical Practice Research Datalink Erectile dysfunction Reference
September 2016 10-Year Outcomes after monitoring, surgery, or radiotherapy for localized prostate cancer Prostate disease Reference
August 2016 Predictive value of serum testosterone for type 2 diabetes risk assessment in men Androgen deficiency and testosterone Reference
July 2016 Quality of care achievements of the Prostate Cancer Outcomes Registry – Victoria Prostate disease Reference
June 2016 It’s not about “Freudian couches and personality changing drugs”: An investigation into men’s mental health help-seeking enablers General Reference
May 2016 Help-seeking experiences of men diagnosed with colorectal cancer: A qualitative study General Reference
April 2016 ‘Marginalised malignancies’: A qualitative synthesis of men’s accounts of living with breast cancer General Reference
April 2016 Sperm telomere length as a parameter of sperm quality in normozoospermic men Male fertility and fatherhood Reference
March 2016 “. . . If you’re not part of the institution you fall by the wayside”: Service providers’ perspectives on moving young men from disconnection and isolation to connection and belonging General Reference
March 2016 Partner status and mental and physical health of independently living men aged 70 years or older General Reference
February 2016 Walking the tightrope: communicating overdiagnosis in modern healthcare General Reference
January 2016 Australian patterns of prostate cancer care: Are they evolving? Prostate disease Reference
December 2015 Positive strategies men regularly use to prevent and manage depression: A national survey of Australian men General Reference
November 2015 Testicular function in a birth cohort of young men Male fertility and fatherhood Reference
November 2015 Psychosocial aspects of ejaculatory dysfunction and male reproduction Erectile dysfunction Reference
October 2015 The prevalence, severity, and correlates of psychological distress and impaired health-related quality of life following treatment for testicular cancer: a survivorship study Testicular cancer Reference
October 2015 Psychological effects of androgen deprivation therapy on men with prostate cancer and their partners Prostate disease Reference
September 2015 Risk factors for erectile dysfunction in a cohort of 108 477 Australian men Erectile dysfunction Reference
September 2015 Fertility preservation in the male pediatric population: factors influencing the decision of parents and children Male fertility and fatherhood Reference
September 2015 Chemohormonal therapy in metastatic hormone-sensitive prostate cancer Prostate disease Reference
August 2015 Responses to a decision aid on prostate cancer screening in primary care practices Prostate disease Reference
July 2015 Sexuality and exercise in men undergoing androgen deprivation therapy for prostate cancer. Prostate disease Reference
July 2015 Oncologic outcomes of penile cancer treatment at a UK supraregional center General Reference
June 2015 Ecological model of Australian Indigenous men’s health Aboriginal and Torres Strait Islander males Reference
June 2015 How successful is TESE-ICSI in couples with non-obstructive azoospermia? Male fertility and fatherhood Reference
May 2015 A randomised controlled trial to evaluate the efficacy of a 6-month dietary and physical activity intervention for patients receiving androgen deprivation therapy for prostate cancer Prostate disease Reference
May 2015 Fruit and vegetable intake and their pesticide residues in relation to semen quality among men from a fertility clinic Male fertility and fatherhood Reference
April 2015 Testosterone replacement therapy and the internet: An assessment of providers’ health-related web site information content Androgen deficiency and testosterone Reference
April 2015 Why do patients regret their prostate cancer treatment? A systematic review of regret after treatment for localized prostate cancer Prostate disease Reference
March 2015 Male coping with cancer-fertility issues: Putting the ‘social’ into biopsychosocial approaches Male fertility and fatherhood Reference
March 2015 People’s willingness to accept overdetection in cancer screening: population survey Prostate disease Reference
February 2015 Prostate cancer and supportive care: A systematic review and qualitative synthesis of men’s experiences and unmet needs Prostate disease Reference
January 2015 Effects of testosterone treatment on glucose metabolism and symptoms in men with type 2 diabetes and the metabolic syndrome: a systematic review and meta-analysis of randomized controlled clinical trials Androgen deficiency and testosterone Reference
January 2015 Perceived barriers and facilitators to physical activity in men with prostate cancer: Possible influence of androgen deprivation therapy Prostate disease Reference
December 2014 How Does Active Surveillance for Prostate Cancer Affect Quality of Life? A Systematic Review Prostate disease Reference
December 2014 Taking responsibility: A psychological profile of men attending a domestic violence group work intervention program in New South Wales, Australia General Reference
November 2014 Understanding men’s attributions of why they ejaculate before desired: An internet study General Reference
October 2014 Low testosterone concentration and atherosclerotic disease markers in male patients With type 2 diabetes Androgen deficiency and testosterone Reference
October 2014 The evolution of sexual dysfunction in young men aged 18-25 years Erectile dysfunction Reference
September 2014 Testosterone and its effects on human male adolescent mood and behavior: A systematic review Androgen deficiency and testosterone Reference
September 2014 Patterns of relapse in patients with clinical stage I testicular cancer managed with active surveillance Testicular cancer Reference
August 2014 Imagining fatherhood: Young Australian men’s perspectives on fathering Male fertility and fatherhood Reference
August 2014 Gender-Role Conflict and Men’s Body Satisfaction: The Moderating Role of Age General Reference
July 2014 A three-protein biomarker panel assessed in diagnostic tissue predicts death from prostate cancer for men with localized disease Prostate disease Reference
July 2014 Finding a segue into sex: Young men’s views on discussing sexual health with a GP Adolescent and Young Adult Males Reference
June 2014 A systematic review of the factors associated with delays in medical and psychological help-seeking among men General Reference
June 2014 Geographic variation in prostate cancer survival in New South Wales Prostate disease Reference
June 2014 Psychosocial risk factors associated with fathers’ mental health in the postnatal period: Results from a population-based study Male fertility and fatherhood Reference
May 2014 Effectiveness of primary androgen-deprivation therapy for clinically localized prostate cancer. Prostate disease Reference
April 2014 Tadalafil for prevention of erectile dysfunction after radiotherapy for prostate cancer: the Radiation Therapy Oncology Group [0831] randomized clinical trial Prostate disease Reference
March 2014 Second cancer risk and mortality in men treated with radiotherapy for stage I seminoma Testicular cancer Reference
February 2014 Increased risk of non-fatal myocardial infarction following testosterone therapy prescription in men Androgen deficiency and testosterone Reference
January 2014 The relationship between male BMI and waist circumference on semen quality: data from the LIFE study Male fertility and fatherhood Reference
December 2013 Prospective associations of concerns about physique and the development of obesity, binge drinking, and drug use among adolescent boys and young adult men Adolescent and Young Adult Males Reference
November 2013 Gonadal Steroids and Body Composition, Strength, and Sexual Function in Men Androgen deficiency and testosterone Reference
October 2013 Global trends in testosterone prescribing, 2000–2011: expanding the spectrum of prescription drug misuse Androgen deficiency and testosterone Reference
September 2013 Diagnostic and outcome differences between heterosexual and nonheterosexual men treated for prostate cancer Prostate disease Reference
August 2013 Factors associated with adherence to physical activity guidelines in patients with prostate cancer Prostate disease Reference
July 2013 Autism and mental retardation among offspring born after in vitro fertilization Male fertility and fatherhood Reference
July 2013 Reference Ranges and Determinants of Testosterone, Dihydrotestosterone, and Estradiol Levels Measured using Liquid Chromatography-Tandem Mass Spectrometry in a Population-Based Cohort of Older Men Androgen deficiency and testosterone Reference
June 2013 Prevalence of the metabolic syndrome and cardiovascular disease risk in chemotherapy-treated testicular germ cell tumour survivors Testicular cancer Reference
June 2013 Trends in Androgen Prescribing in the United States, 2001 to 2011 Androgen deficiency and testosterone Reference
May 2013 One patient out of four with newly diagnosed erectile dysfunction is a young man – worrisome picture from the everyday clinical practice Erectile dysfunction Reference
May 2013 The feasibility of fertility preservation in adolescents with Klinefelter syndrome Androgen deficiency and testosterone Reference
April 2013 Association between testosterone levels and risk of future rheumatoid arthritis in men: a population-based case-control study Androgen deficiency and testosterone Reference
April 2013 Long-term functional outcomes after treatment for localized prostate cancer Prostate disease Reference
March 2013 Predictors of health-related quality of life and adjustment to prostate cancer during active surveillance Prostate disease Reference
February 2013 Erectile dysfunction severity as a risk marker for cardiovascular disease hospitalisation and all-cause mortality: A prospective cohort study Erectile dysfunction Reference
January 2013 Evaluation of the pilot phase of an Aboriginal and Torres Strait Islander Male Health Module General Reference
December 2012 Patients’ expectations of screening and preventive treatments General Reference
November 2012 Sexual dysfunctions among young men: prevalence and associated factors Adolescent and Young Adult Males Reference
October 2012 Population-based case-control study of recreational drug use and testis cancer risk confirms an association between marijuana use and nonseminoma risk Testicular cancer Reference
September 2012 Why don’t healthcare professionals talk about sex? A systematic review of recent qualitative studies conducted in the United Kingdom General Reference
August 2012 Prostate-specific antigen screening for prostate cancer and the risk of overt metastatic disease at presentation Prostate disease Reference
July 2012 Cumulative parenthood rates in 1735 couples: impact of male factor infertility Male fertility and fatherhood Reference
June 2012 The Influence of testosterone suppression and recovery on sexual function in men with prostate cancer: Observations from a prospective study in men undergoing intermittent androgen suppression Prostate disease Reference
May 2012 Association between smoking cessation and sexual health in men Erectile dysfunction Reference
April 2012 Improved fertility preservation care for male patients with cancer after establishment of formalized oncofertility program Male fertility and fatherhood Reference
March 2012 Prostate-specific antigen levels in men aged 70 years and over: findings from the CHAMP study Prostate disease Reference
March 2012 Smaller genitals at school age in boys whose mothers were exposed to non-persistent pesticides in early pregnancy Male fertility and fatherhood Reference
February 2012 Pregnancy rate after vasectomy reversal in a contemporary series: influence of smoking, semen quality and post-surgical use of assisted reproductive techniques. Male fertility and fatherhood Reference
December 2011 Use of laptop computers connected to internet through Wi-Fi decreases human sperm motility and increases sperm DNA fragmentation Male fertility and fatherhood Reference
November 2011 Impact of androgen deprivation therapy on depressive symptoms in men with nonmetastatic prostate cancer Prostate disease Reference
October 2011 Prediction of erectile function following treatment for prostate cancer Erectile dysfunction Reference
September 2011 The legacy of sperm banking: how fertility monitoring and disposal of sperm are linked with views of cancer treatment Male fertility and fatherhood Reference
August 2011 Confirmation of family cancer history reported in a population-based survey Prostate disease Reference
July 2011 Effect of intensive glycemic therapy on erectile function in men with Type 1 diabetes Erectile dysfunction Reference
June 2011 Physical activity and survival after prostate cancer diagnosis in the Health Professionals Follow-up Study Prostate disease Reference
May 2011 Factors that influence the childbearing intentions of Canadian men Male fertility and fatherhood Reference
April 2011 Randomised prostate cancer screening trial: 20 year follow-up Prostate disease Reference
March 2011 Antioxidants for male subfertility Male fertility and fatherhood Reference
February 2011 Obesity and age affect male fertility potential Male fertility and fatherhood Reference
December 2010 Overtreatment of men with low-risk prostate cancer and significant morbidity Prostate disease Reference
November 2010 Low serum testosterone levels are poor predictors of sexual dysfunction Androgen deficiency and testosterone Reference
October 2010 Prostate specific antigen concentration at age 60 and death or metastasis from prostate cancer: case-control study Prostate disease Reference
September 2010 Predictors of psychosocial distress 12 months after diagnosis with early and advanced prostate cancer Prostate disease Reference
August 2010 Adverse events associated with testosterone administration Androgen deficiency and testosterone Reference
July 2010 Mortality results from the Göteborg randomised population based prostate-cancer screening trial Prostate disease Reference
June 2010 Determinants of erectile dysfunction in type 2 diabetes Erectile dysfunction Reference
May 2010 The Effects of Growth Hormone on Body Composition and Physical performance in Recreational Athletes. A Randomized Trial General Reference
April 2010 Do anxiety and distress increase during active surveillance for low risk prostate cancer? Prostate disease Reference
March 2010 Age-specific risk of incident prostate cancer & risk of death from pr cancer defined by the number of affected family members Prostate disease Reference
February 2010 Counterfeit phosphodiesterase type 5 inhibitors pose significant safety risks Erectile dysfunction Reference
January 2010 Men’s health literacy: advancing evidence and priorities General Reference